Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,741
Tocris Bioscience™ HIOC, >98%
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CAS: 314054-36-9 Molecular Formula: C16H19N3O3
| CAS | 314054-36-9 |
|---|---|
| Molecular Formula | C16H19N3O3 |
1,742
Tocris Bioscience™ CA 074
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CAS: 134448-10-5 Molecular Formula: C18H29N3O6
| CAS | 134448-10-5 |
|---|---|
| Molecular Formula | C18H29N3O6 |
1,743
Tocris Bioscience™ FTIDC
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Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonist
1,744
Tocris Bioscience™ PF 06465469
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CAS: 1407966-77-1 Molecular Formula: C30H33N7O2
| CAS | 1407966-77-1 |
|---|---|
| Molecular Formula | C30H33N7O2 |
1,745
Tocris Bioscience™ MKT 077
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CAS: 147366-41-4 Molecular Formula: C21H22ClN3OS2
| CAS | 147366-41-4 |
|---|---|
| Molecular Formula | C21H22ClN3OS2 |
1,746
Tocris Bioscience™ CC4
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High affinity and subtype-selective α6β2 and α4β2 nAChR partial agonist
| Target | Additional Nicotinic (a4b2) Receptor Compounds |
|---|---|
| CAS | 492-02-4 |
| Purity | >98% |
| Chemical Name or Material | (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C24H30N4O2 |
| Formula Weight | 406.52 |
1,747
Tocris Bioscience™ SK 575-NEG
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Negative control for SK 575 (Cat. No. 7583)
1,748
Tocris Bioscience™ SMER 28
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CAS: 307538-42-7 Molecular Formula: C11H10BrN3
| CAS | 307538-42-7 |
|---|---|
| Molecular Formula | C11H10BrN3 |
1,749
Tocris Bioscience™ TC-S 7005
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CAS: 1082739-92-1 Molecular Formula: C21H17N3O3
| CAS | 1082739-92-1 |
|---|---|
| Molecular Formula | C21H17N3O3 |
1,750
Tocris Bioscience™ E 64d
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CAS: 88321-09-9 Molecular Formula: C17H30N2O5
| CAS | 88321-09-9 |
|---|---|
| Molecular Formula | C17H30N2O5 |
1,751
Tocris Bioscience™ LRRK2-IN-1
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CAS: 1234480-84-2 Molecular Formula: C31H38N8O3
| CAS | 1234480-84-2 |
|---|---|
| Molecular Formula | C31H38N8O3 |
1,752
Tocris Bioscience™ JW 74
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Wnt pathway inhibitor
| CAS | 863405-60-1 |
|---|---|
| Solubility | Soluble to 100mM in DMSO |
| Purity | >99% |
| Chemical Name or Material | 4-[4-(4-Methoxyphenyl)-5-[[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]thio]-4H-1,2,4-triazol-3-yl]-pyridine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C24H20N6O2S |
| Formula Weight | Observed MW: 456.52 |
1,753
Tocris Bioscience™ (R)-Citalopram oxalate
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Enantiomer of escitalopram oxalate (Cat. No. 1427)
| Target | 5-HT Transporter Inhibitors |
|---|---|
| CAS | 219861-53-7 |
| Purity | >98% |
| Chemical Name or Material | (-)-(R)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C20H21FN2O.C2H2O4 |
| Formula Weight | 414.43 |
1,754
Tocris Bioscience™ Imatinib mesylate
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Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
1,755
Tocris Bioscience™ tri-GalNAc biotin
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Biotinylated ASGPR ligand for LYTAC research and development